Advanced Joint Care

for Your Horse

Designed to reduce friction and protect cartilage, Noltrex®Vet provides unique support for long-term joint health.

Advanced Joint Care for Your Horse

Designed to reduce friction and protect cartilage, Noltrex®Vet provides unique support for long-term joint health.

What is Noltrex®Vet?

Noltrex®Vet is a veterinarian-administered synthetic joint lubricant (4% polyacrylamide hydrogel). It reduces friction in treated joints and forms a protective layer on the cartilage, promoting smoother movement and long-lasting comfort.

Whether your horse is a top performer or just needs extra support as they age, Noltrex®Vet offers a unique solution to keep them active and comfortable.

Recognized by Trusted Equine Resources

Why Choose Noltrex®Vet?

Noltrex®Vet supports an optimal environment for long-term joint health by delivering advanced, longer-lasting lubrication to minimize additional stress on cartilage.

Noltrex®Vet works differently by:

Reducing friction within the joint for smoother movement

Forming a protective layer on cartilage to help minimize wear and tear

Providing longer-lasting support to maintain comfort and mobility

What Makes Noltrex®Vet Unique?

Science-Backed Innovation for the Freedom to Move Comfortably

fawn pug lying on floor

Reduces Friction to Support Joint Health

When joint fluid becomes thinner, friction increases, leading to discomfort and potential tissue damage. Noltrex®Vet works by reducing this friction, protecting the cartilage, and helping your horse move more comfortably.

Image Source: Varela et al., 2024. EVCNA.

man in green jacket holding white and brown short coated dog

Targeted Lubrication for Cartilage Protection

Noltrex®Vet forms a protective lubricating layer on cartilage, helping to reduce wear and tear caused by friction. This unique ability ensures targeted support where it’s needed most.

person pouring water on womans hair

Suitable for Repeat Dosing and Long-Lasting Support

Noltrex®Vet’s unique synthetic formulation is slowly removed from the joint and surrounding tissues, providing long-lasting support but also making it suitable for repeat dosing throughout your horse’s lifetime.

Hear from Veterinarians & Horse Owners: Real Results with Noltrex®Vet

At Noltrex®Vet, we believe in letting results speak for themselves. Whether it is helping equine athletes stay at peak performance or providing long-term joint support for beloved companions, our customers have experienced the difference firsthand.

Read what veterinarians, trainers, and horse owners have to say about how Noltrex®Vet has improved mobility, extended careers, and enhanced the quality of life for horses of all disciplines.

Hear from Veterinarians & Horse Owners:

Real Results with Noltrex®Vet

At Noltrex®Vet, we believe in letting results speak for themselves. Whether it is helping equine athletes stay at peak performance or providing long-term joint support for beloved companions, our customers have experienced the difference firsthand.

Read what veterinarians, trainers, and horse owners have to say about how Noltrex®Vet has improved mobility, extended careers, and enhanced the quality of life for horses of all disciplines.

0%

97% of vets foresee increasing the use of Noltrex Vet to replace traditional HA treatments. Why? It provides lasting lubrication, helping your horse move comfortably and perform their best.

*2023 Advanced User Survey representing 4,000+ cases

0%

60% of veterinarians recommend Noltrex Vet for routine sports medicine cases. Protect your horse’s joints before issues escalate, ensuring a healthier, happier future.

*2023 Advanced User Survey representing 4,000+ cases

0%

98.5% of Vets say Noltrex®Vet is the go-to solution for managing chronic, late-stage osteoarthritis. Give your horse the comfort they deserve, even in the toughest conditions.

*2023 Advanced User Survey representing 4,000+ cases

0%

80.7% of horses treated with Noltrex Vet experience 2-4x longer clinical effects compared to other treatments. More relief, fewer treatments—because your time and your horse’s comfort matter.

*2023 Advanced User Survey representing 4,000+ cases

Testimonials

Leah Patipa, DVM

Paddock Equine Veterinary Services, Wellington, FL

"Initially we used Noltrex®Vet on cases where we were struggling to keep them sound with steroids and biologics. In one case within one injection of Noltrex®Vet, he was sound for over 6 months. After these types of cases, Noltrex®Vet has become a go-to tool in our practice for managing performance horses as a maintenance treatment. We have had very good success using Noltrex®Vet in both low and high motion joints."

Shannon Dueck

International Grand Prix Dressage Rider, Loxahatchee, FL

"We had done almost every treatment that we could during a year of rehabilitation. It was Noltrex®Vet that was a game changer for us. Within a month of injection, he was almost 100% sound. Within two months, with increased training and strength, he became 100% sound and went on to compete at the Grand Prix level."

Lisa D. (Owner)

"This was literally a lifesaver for my gelding with high front ringbone. He went from dead lame to sound immediately for a year. ❤️ He was injected two more times with a year in between till he was completely fused and could no longer be injected. A godsend for us both."

Pamela L. (Owner)

"This gave my gelding an opportunity to run barrels another 7 years after an injury to the knee."

Terri A. (Owner)

"Love it! We use it for my gelding’s coffin joint above his bone cyst – Works Great."

Kathryn F. (Owner)

"Noltrex®Vet has been a game changer for my older gelding. He’s 22 this year and he can't have steroid injections. He’s had 2 Noltrex®Vet injections and both lasted over a year."

Melanie W. (Owner)

"My horse would have been retired 4 years ago if Noltrex®Vet wasn’t available. She has 2 fetlock surgeries years ago. Other treatments weren’t working anymore. She’s 23 and doing really well with Noltrex®Vet."

Frequently Asked Questions

Have questions about Noltrex®Vet? Explore our FAQs to find quick and reliable answers!

What is Noltrex®Vet?

Noltrex®Vet is a veterinarian-administered synthetic joint lubricant (4% polyacrylamide hydrogel) that reduces friction in treated joints. Noltrex®Vet was designed to mimic healthy joint fluid.

How does Noltrex®Vet compare to hyaluronic acid?

Both Noltrex®Vet and hyaluronic acid help to reduce friction in the joint. Noltrex®Vet is very effective at reducing friction and lasts in the joint significantly longer than hyaluronic acid. Noltrex®Vet also forms a protective lubricating layer on cartilage, offering targeted protection where your horse needs it most.

What makes Noltrex®Vet different from other joint products?

Noltrex®Vet stands out by providing advanced lubrication that reduces friction to protect cartilage. This physical cartilage protection supports an optimal environment for long-term joint health and can be used alongside other therapies that address pain, inflammation, and tissue healing. Your veterinarian will determine the best treatment plan based on your horse’s specific needs.

Can Noltrex®Vet keep my horse sound for longer periods?

While every horse is different, veterinarians generally report that the clinical effects of Noltrex®Vet last 2-4 times longer than treatments without it. Factors such as the degree and type of tissue damage, how hard they work, aging, and others, can influence how long the benefits last.

How long does Noltrex®Vet last?

A single dose of Noltrex®Vet remains in the joint for around 30-60 days. This duration may be longer, in some cases, when subsequent dosing is utilized. Horses may experience benefits lasting 6 to 24 months, depending on individual factors.

Can Noltrex®Vet be combined with other treatments?

Maintaining joint health often requires a multi-modal approach. Noltrex®Vet can be used alongside other treatments that manage inflammation, pain, and tissue healing, such as steroids or orthobiologics. In cases where inflammation is controlled, Noltrex®Vet may also be used as a monotherapy. Your veterinarian will determine the best combination of therapies and the optimal timing for your horse’s specific needs.

What joints can be treated with Noltrex®Vet?

Noltrex®Vet can be used in any synovial joint where your horse requires supplemented lubrication. It has demonstrated clinical efficacy in high-motion joints like fetlocks, stifles, and coffin joints, as well as lower-motion joints like the lower hock and pastern joints.

How quickly will my horse improve after treatment?

While horses may respond at different rates, many owners see gradual improvement over 1-3 weeks. If your horse shows improvement but the lameness is not completely resolved, a follow-up injection may be considered after 30 days if recommended by your veterinarian.

Ask your Vet About

Noltrex®Vet

Noltrex®Vet requires a thorough evaluation of your horse’s condition to ensure suitability for injection by precise intra-articular administration. This device is limited to the sale by or on the order of a licensed veterinarian. Risks associated with Noltrex®Vet are inherent to the administration route.

Stay Connected with Noltrex®Vet

Subscribe for helpful tips, product updates, and more to keep your horse moving comfortably.

By submitting your email address, you are opting in to receive marketing communications from Nucleus ProVets and agree to the Terms and Conditions and Privacy Policy.

Do you have a Noltrex®Vet Success Story?

Has Noltrex®Vet made a difference for your horse? We'd love to hear your story!

Share your experience with us.